Femara
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Femara is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer.
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Medications and Prescriptions
Generic name: Letrozole
Product Brand Name: Femara ®
1. Description: Femara is an oral, anti-estrogen drug that is used for treating postmenopausal women with breast cancer. Femara was approved by the U.S. Food and Drug Administration for use in 1997.
2. Femara is Prescribed for: Femara is used to treat postmenopausal women with breast cancer that is resistant to the more commonly-used anti-estrogen medications such as tamoxifen (Nolvadex).
3. Drug Mechanism: The growth of some breast cancers in postmenopausal women is promoted by estrogens that circulate in the blood, and the adrenal glands are the main source of these circulating estrogens. Letrozole inhibits the enzyme in the adrenal glands (aromatase) that produces the estrogens, estradiol and estrone.
4. Dosage Form: Femara generally is taken once daily, with or without food (one 2.5-mg tablet a day). Continue until tumor progression is evident. Dosage adjustment is not needed in renal impairment if CCR is greater than or equal to 10 mL/min.
5. Drug Interactions: There are no known drug interactions with Femara.
6. Pregnancy: Femara damages the fetus. It should not be taken by pregnant women. Femara is meant to be used only by women who are no longer able to have children.
7. Nursing Mothers: It is not known if Femara is secreted into breast milk.
8. Alcohol Considerations: Ask your doctor for information on how much is safe to drink.
9. Possible Side Effects: The most common side effects with Femara are nausea, vomiting, fatigue, headache, muscle aches, diarrhea, constipation, and chest pain. The likelihood of side effects is lower than with other drugs used more commonly in patients with breast cancer that is resistant to treatment with anti-estrogens.
10. Storage: Capsules should be stored at room temperature, 15-30°C (59-86°F). Keep this medication out of reach of children. Do not store in the bathroom or in other damp places. Heat or moisture may cause the medicine to break down Throw away any medication that is outdated or no longer needed.
11. Package Size and Type: Tablets: 2.5mg.
12. Where can I get more information on Femara?
a) U.S. National Library of Medicine and National Institutes of Health
b) WebMD Corporation
Caution! Before starting to take this medicine, it is vital that you should consult your doctor! Do not use it on your own initiative, without medical advice.
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